FIBRINOGEN

Kit Fibrinogen

Reagent for quantitative determination of Fibrinogen in human plasma

The method uses Von Clauss and al. method.

In the presence of an excess of thrombin, the time of formation of the fibrin clot in the plasma (pre-diluted) is reversely proportional to the amount of fibrinogen in the sample. The clotting time is measured at 37°C.

 

Clinical interest

Fibrinogen is a glycoprotein (340 KDa) synthesised by liver and present in the plasma at a level within 2 to 4 g/L.
The concentration of fibrinogen is increased in infections, estrogens ingestion, tissue necrosis, obesity, pregnancies and diabetes. An increase of fibrinogen is also involved as a risk factor for coronary artery disorders and cerebrovascular diseases.
A decrease of fibrinogen in plasma is associated with:
- liver diseases (cirrhosis, jaundice)
- Fibrinolysis or disseminated intravascular coagulation (DIC)

Presentation and Technical Data Sheet

CODE Presentation Technical data sheet MSDS
FI02 R1 : 5 x 2mL
R2 : 1 x 60mL (Dilution buffer)
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FI05 R1 : 10 x 5mL
R2 : 1 x 125mL (Dilution buffer)
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